"Flaw" mutator isn't even a flaw to be honest. As defender you pick plasma if you don't want to be preatorian, as runner also this, as spitter you are taking tackle and as drone you are taking dmg. It's just straight boost.
It would be better to have mutators that counter each other: Health boost - Armor nerf, Armor boost - Health Nerf, Dmg boost - speed nerf, Speed boost - Dmg nerf, etc.